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A study
testing low-dose hormone replacement therapy (HRT) on the
effects of skin wrinkling in postmenopausal women is underway
at the University of Louisville and Bluegrass Clinical Research,
Inc. in Louisville, Kentucky.
The study
is designed to evaluate the safety and effectiveness of an
investigational, low-dose oral HRT as a possible means for
controlling and improving age-related skin wrinkling. Women
eligible to participate in the study must be postmenopausal
or have ceased menstruating for at least six months; be between
the ages of 45 and 65; and must not be taking HRT currently.
Participants
approved for the study will undergo a complete physical and
pelvic examination including a Pap smear, vaginal ultrasound
and mammogram. They will also be evaluated by a dermatologist
and undergo skin evaluations focusing on fine lines and coarse
wrinkles, laxity, sagging, texture and dryness. All procedures
will be performed free of charge to the participants.
"One
of the more common concerns that women have about menopause
is their appearance," said Dr. Steven T. Nakajima, associate
professor and division chief, Division of Reproductive Endocrinology
and Infertility at the University of Louisville. "That's
one of the reasons we're conducting the HRT study -- to look
at skin aging and whether this investigational, low dose HRT
can control or reduce age-related skin wrinkling."
Women
interested in participating in the study can call: 1-877-HRT-8390.
Source:
Medical Week staff,
week of April 21, 2002
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