Save 50% with Home Delivery!

Bladder Control
Breast Cancer
Colorectal Cancer
Eye Disease
Acid Reflux - Ulcers
Heart Disease
Joint Replacement
Lung Cancer
Prostate Cancer
Skin Cancer
Senior Health Week: Colorectal Cancer
Health News You Can Use •

Colorectal Cancer News:

Raltitrexed Far More Toxic Than Chemotherapy for Advanced Colorectal Cancer Patients

The antimetabolite drug raltitrexed appears to be less desirable than two fluorouracil-based chemotherapy regimens for treating patients with advanced colorectal cancer, according to a report in The Lancet.

British researchers reported that in a study of 905 patients, median survival time was 302 days for patients on the Lokich chemotherapy regimen and 294 days for patients on the de Gramont chemotherapy regimen, but only 266 days for patients receiving raltitrexed.

The researchers also reported that there were 18 treatment-related deaths among patients taking raltitrexed as a result of combined gastrointestinal and haematological toxicity, compared to two deaths on the Lokich regimen and one on de Gramont regimen

Further, they said patients' assessment of quality of life during treatment showed that raltitrexed was inferior to the fluorouracil-based regimens, especially in terms of providing symptomatic relief and enabling the patient to function.

"Although raltitrexed-related toxicity has been reported in all previous trials, this trial has highlighted the problem because of the low toxicity of the comparators," the researchers noted.

Source: Colorectal Cancer Week of May 12, 2002


Over 50?  Great rates are a click away!



About This Site
Privacy Policy
Advertising Policy
Contact Us

USE OF THIS SITE SIGNIFIES ACCEPTANCE OF THIS USER AGREEMENT: The information provided in this and our other sites is for educational purposes only, and it is not intended nor implied to be a substitute for professional medical advice. Always consult your own physician or healthcare provider with any questions you may have regarding a medical condition. Hypertext links to other sites are for the convenience of our Web site viewers and do not constitute any endorsement. We are not responsible for the content of linked sites in any way. This site is intended for personal use only and may not be used for any commercial purpose.