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Chinese
herbals are being tested by researchers at the University
of Connecticut as a potential therapy for hot flashes experienced
by some breast cancer survivors.
Hormone
replacement therapy has been the most common treatment for
hot flashes, but women who have had breast cancer are advised
not to take hormone replacement therapy as it has been shown
to increase the risk of breast cancer recurrence.
"Many
women, who have been treated for breast cancer, come into
my office justifiably complaining of frequent, extremely uncomfortable,
and often embarrassing hot flashes," said Dr. Jonathan
Sporn, medical oncologist and lead researcher of the study.
"The
only non-hormonal treatment that's been shown to help is the
antidepressant venlafaxine, which may have side effects,"
said Sporn. "Generally, patients have been disappointed
with over-the-counter herbal therapies, but I've had several
patients report positive benefits from personalized Chinese
herbal therapy programs."
Sporn
has begun a study to test the effectiveness of an herbal program,
comparing it with venlafaxine or a placebo. Chinese herbologist
Laura Mignosa from the Connecticut Institute for Herbal Studies
is assisting with the study.
Chinese
medicine is based on determining patterns of disharmonies
in the body through observation, listening, questioning, touching
and smelling, explained Mignosa. "Yin-yang is the basic
principle of balance in the health of the body. Yang represents
the raising or heating properties of the body and yin the
fluid or cooling energy."
Mignosa
will prepare mixtures of several herbs based on individual
patient assessments. "You have to determine whether there's
an excess in Yin or Yang when balance is disrupted. Breast
cancer survivors have several common patterns, each of which
suggests a potential therapeutic role for certain Chinese
herbs," said Mignosa.
Women
who have a history of breast cancer, and are either currently
taking tamoxifen or have premature menopause induced by chemotherapy,
may be eligible to participate in the study. Study participants
will be on each treatment for a period of two months. They
will answer weekly questionnaires and make periodic visits
to the University of Connecticut Health Center.
Source:
Breast Cancer
Week of July 21, 2002

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