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Senior Health Week: Acid Reflux - Ulcers
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Acid Reflux - Ulcer News:

Study Finds Prevacid® Highly Effective in Treating Erosive Esophagitis

Prevacid® (lansoprazole) is highly effective in treating erosive esophagitis, a severe form of gastroesophageal reflux disease (GERD), according to a study published in the journal Drugs.

Erosive esophagitis is characterized by frequent and persistent heartburn two or more days per week.

"Continuous maintenance therapy is very important to a patient's management of erosive esophagitis," said Dr. James Freston, Professor of Medicine at the University of Connecticut Health Center and author of the study. "Without treatment, a majority of patients may experience esophagitis relapse within 12 months."

Freston reviewed an extensive amount of clinical data regarding Prevacid's safety and effectiveness in providing continuous relief of symptoms during chronic therapy and maintaining healing of erosive esophagitis.

Up to 79 percent of patients taking 15 mg of Prevacid daily and up to 90 percent of patients taking 30 mg of Prevacid daily remained healed after one year. Up to 24 percent of the groups taking a placebo remained healed at 12 months. There were low rates of relapse in the patients being treated with Prevacid.

A one-year study comparing Zantac (ranitidine) to Prevacid showed patients with erosive esophagitis who were taking Prevacid remained healed for a significantly longer period of time than those taking Zantac. Also, Prevacid was significantly more effective than Zantac in providing complete relief of both daytime and nighttime heartburn.

Prevacid is a proton pump inhibitor and works by inhibiting gastric acid secretion. Zantac, a histamine-2 receptor antagonist, provides relief by decreasing the amount of acid the stomach produces.

Source: Medical Week staff, week of May 26, 2002



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